From 1958 to October 1977, 294 cases of acquired heart disease were operated. There were 68 cases of pericardium, 3 trauma, 2 foreign body, one cardiac thrombus, 3 atrial myxoma, 2 left atrial and 1 right atrial, 2 Budd-Chiari syndrome, and 214 valvular heart disease.
Out of 214 cases of valve operation 73 valves were replaced in 64 patients.
Male to female ratio was 1.46:1. The youngest age was 14 years in male and 18 in female. The oldest was 54 years in male and 52 in female.
Fifty-five cases of single valve were replacement cases which consist of 7 mitral and aortic and 2 mitral and tricuspid valves.
Six varieties of prosthetic valves, 3 ball and e disc type and 3 kinds of xenograft tissue valves were utilized.
Beall, Bjork-Shiley and Starr-Edwards prosthetic valves and Hancock valves were used mainly.
For single valve 34.5% and for double valve replacement 44% mortality were noted.
There were 23 operative deaths out of 64 patients, over all mortality rate of 36.9%.
Mortality for mitral valve replacement was 29.5%. But in recent 12 consecutive cases one death occurred, showing 8.3% mortality.
In earlier days thrombocyte anti-adhesive drug dipyramidole-persantin-asprin and/or SP 54 were adminstered. But in recent cases after heparinization, coumadin and Persantin were prescribed routinely.
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